Chemical reactions occur at lightning speed as electrons jump between atomic nuclei, making it virtually impossible to map every separate step in chemical processes involving large molecules like proteins.

Powerful computer models, first developed by the three scientists in 1970s, offer a new window onto such reactions and have become a mainstay for researchers in thousands of academic and industrial laboratories around the world.

via Scientists who took chemistry into cyberspace win Nobel Prize – chicagotribune.com.